| 1 | Dr. M. Muni Swamy | M.S., FICS | 07-08-1954 | 04-11-1956 |
| 2 | Dr. S. Venkateswarlu | MBBS, DMRT | 05-11-1956 | 09-05-1963 |
| 3 | Dr. K. Kodandaramiah | M.D. | 10-05-1963 | 01-07-1964 |
| 4 | Dr. S. Ramachandra Rao | MBBS, MRCP | 02-07-1964 | 14-07-1965 |
| 5 | Dr. K. Kodandaramiah | M.D. | 15-07-1965 | 16-04-1968 |
| 6 | Dr. V.S. Raghunadhan | M.D. | 17-04-1968 | 22-12-1968 |
| 7 | Dr. L. Suryanarayana | M.S., FICS | 23-12-1968 | 02-02-1974 |
| 8 | Dr. N. Veerabhadra Reddy | M.S., FICS | 03-02-1974 | 30-06-1975 |
| 9 | Dr. P. Lakshman Rao | M.D., FICA | 01-07-1975 | 31-10-1975 |
| 10 | Dr. Y.R. Reddy | M.D., MAMS | 01-11-1975 | 24-04-1977 |
| 11 | Dr. P. Lakshman Rao | M.D., FICA | 25-04-1977 | 28-02-1983 |
| 12 | Dr. K. Prasunamba | M.D., DGO | 01-03-1983 | 09-06-1983 |
| 13 | Dr. K. Veerabhadra Rao | M.S. | 10-06-1983 | 10-12-1983 |
| 14 | Dr. N.V.S. Chowdary | M.S. | 11-12-1983 | 25-02-1984 |
| 15 | Dr. V. Ramanamma | M.D., DGO | 26-02-1984 | 01-06-1985 |
| 16 | Dr. C. Mallikharjuna Rao | M.D. | 02-06-1985 | 30-06-1986 |
| 17 | Dr. N.V.S. Chowdary | M.S., FICS | 01-07-1986 | 15-11-1986 |
| 18 | Dr. K. Vengala Rao | M.S., DO | 16-11-1986 | 30-06-1987 |
| 19 | Dr. M. Krishnamurthy | M.D., DCH | 01-07-1987 | 08-01-1988 |
| 20 | Dr. T. Sarojini | M.D., DGO | 09-01-1988 | 11-08-1991 |
| 21 | Dr. R.B. Krishnamurthy | M.S., FRCS | 12-08-1991 | 30-11-1992 |
| 22 | Dr. S. Koteswara Rao | M.S., DO | 01-12-1992 | 30-06-1993 |
| 23 | Dr. P. Venkateswarlu | M.D. | 01-07-1993 | 16-05-1994 |
| 24 | Dr. T. Chennamallappa | M.S. | 17-05-1994 | 30-06-1994 |
| 25 | Dr. G. Venkat Ramaiah | M.S. | 01-07-1994 | 07-09-1994 |
| 26 | Dr. P. Venkateswarlu | M.D. | 08-09-1994 | 20-11-1994 |
| 27 | Dr. M. Markadeya | M.S. | 21-11-1994 | 23-02-1995 |
| 28 | Dr. G. Venkataramaiah | M.S. | 24-02-1995 | 31-05-1995 |
| 29 | Dr. G. Rani | M.D., DCH | 01-06-1995 | 06-07-1995 |
| 30 | Dr. M. Venkatesh | M.D. | 07-07-1995 | 31-10-1996 |
| 31 | Dr. M. Leelavathi | M.D. (ENT) | 01-11-1996 | 16-02-1997 |
| 32 | Dr. V. Sambasiva Rao | M.D. | 17-02-1997 | 28-02-1997 |
| 33 | Dr. M. Leelavathi | M.D. (ENT) | 01-03-1997 | 30-09-1997 |
| 34 | Dr. V. Kamala Jayaram | M.D., DGO | 01-10-1997 | 31-05-1998 |
| 35 | Dr. V.R. Jayaram | M.D. | 01-06-1998 | 17-09-1998 |
| 36 | Dr. Sarada Acharya | M.D., DGO | 18-09-1998 | 22-11-1998 |
| 37 | Dr. K. Anji Reddy | M.S. | 23-11-1998 | 15-01-1999 |
| 38 | Dr. Sarada Acharya | M.D. | 16-01-1999 | 28-01-1999 |
| 39 | Dr. V.R. Jaya Ram | M.S., FICS | 29-01-1999 | 31-03-1999 |
| 40 | Dr. K. Anji Reddy | M.S. | 01-04-1999 | 02-05-2000 |
| 41 | Dr. S. Venkata Swamy | M.D. | 02-05-2000 | 24-06-2000 |
| 42 | Dr. K. Nageswara Rao | M.D. | 25-06-2000 | 31-12-2000 |
| 43 | Director of Medical Education (Special) | — | 01-01-2001 | 31-03-2001 |
| 44 | Dr. Md. Fayaz Ahmed | M.S. | 01-04-2001 | 31-05-2004 |
| 45 | Dr. P. Bhagavannarayana | M.D., DGO | 01-06-2004 | 28-02-2006 |
| 46 | Dr. K.K.D. Malleswara Rao | M.D. | 01-03-2006 | 16-06-2006 |
| 47 | Dr. B. Mohan Rao | M.D. | 17-06-2006 | 31-03-2008 |
| 48 | Dr. (Mrs.) M. Sobha Mohan | M.D. | 11-10-2006 | 10-12-2006 |
| 49 | Dr. Y. Prabhakara Rao | M.S. (ENT) | 06-01-2007 | 20-02-2007 |
| 50 | Dr. A. Krishna Rao | M.D. | 09-06-2007 | 14-03-2008 |
| 51 | Dr. D. Phani Bhushan | M.D., DPM | 01-04-2008 | 31-08-2011 |
| 52 | Dr. Challa Mohan Rao | M.S. (Ophth) | 01-09-2011 | 31-12-2013 |
| 53 | Dr. G. Sailabala | M.D. | 01-01-2014 | 23-02-2014 |
| 54 | Dr. T. Venu Gopal Rao | M.D., DA | 24-02-2014 | 25-09-2015 |
| 55 | Dr. D.S. Raju Naidu | M.D., DMRT | 26-09-2015 | 31-08-2019 |
